Associations of HLA DRB1 Alleles with Igg Oligoclonal Bands and Their Influence on Multiple Sclerosis Course and Disability Status
نویسندگان
چکیده
منابع مشابه
Associations of HLA DRB1 alleles with IgG oligoclonal bands and their influence on multiple sclerosis course and disability status.
BACKGROUND AND AIM Oligoclonal bands (OCB) may be associated with the genes of HLA complex, which allows to consider the possible interaction of genetic and immunological factors and its importance in the development and progression of multiple sclerosis (MS). The aim of this study was to evaluate the associations between HLA DRB1 alleles and oligoclonal bands (OCBs) in the disease course and d...
متن کاملCorrelation of the IgG index and oligoclonal bands in the CSF of patients with multiple sclerosis
Klíčová slova oligoklonální pásy – mozkomíšní mok – IgG index – roztroušená skleróza Abstract Objective: The aim of this study was to assess the correlation between IgG index values and the number of the oligoclonal IgG bands (OCB) in the cerebrospinal fluid (CSF) of patients with multiple sclerosis (MS). Material and Methods: The set of 150 patients consisted of 41 males and 109 females (aged ...
متن کاملMore on oligoclonal bands and diagnosis of multiple sclerosis.
A When we consider that creatinine and uric acid, for example, are excreted in concentrations of about 15 and 5 mmoLfL, we can already observe positive biases caused by these interferencesat a sample:reagent volume ratio of 1:5 (1). However, this ratio does not yet permit measurement of microalbuminuria. Thus, the interferingreactions of urinary components with bromphenol blue preclude use of t...
متن کاملOligoclonal bands and the IgG index in multiple sclerosis: uses and limitations.
The relationship between two tests commonly used in the investigation of multiple sclerosis (MS), the IgG index and oligoclonal bands, has been assessed. Using an immunoblotting technique specific for IgG, analysis of cerebrospinal fluid for oligoclonal bands was found to provide greater diagnostic sensitivity than the IgG index without any loss of specificity. In patients without oligoclonal b...
متن کاملCSF -- oligoclonal bands in multiple sclerosis.
The present paper is concerned with a correlation between clinical parameters of multiple sclerosis and different agar gel electrophoretical patterns in CSF. The agar gel electrophoresis represents clearly the most sensitive method for the demonstration of oligoclonal bands in CSF.
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ژورنال
عنوان ژورنال: Journal of Neurology & Neurophysiology
سال: 2014
ISSN: 2155-9562
DOI: 10.4172/2155-9562.1000273